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. 2010 Oct 28;66(Pt 11):1453–1457. doi: 10.1107/S1744309110032343

Table 2. Profiling of proteolytic activities in IRS-2 protein preparation.

Substrate Protease type (catalytic class) Proteolytic activity Inhibitor sensitivity
Z-Phe-Arg-AMC Papain-like (cysteine) Yes E64
  Trypsin-like (serine)   Pefabloc
MeoSuc-Ala-Ala-Pro-Val-AMC Elastase-like (serine) No  
Z-Gly-Gly-Leu-AMC Chymotrypsin-like (serine) Yes Pefabloc
Suc-Ala-Ala-Pro-Phe-AMC Chymotrypsin-like (serine) No  
Suc-Leu-Tyr-AMC Calpain-like (cysteine) Yes E64
  Chymotrypsin-like (serine)   Pefabloc