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. 2010 Nov;5(11):1981–1987. doi: 10.2215/CJN.03450410

Table 3.

AUC and Cmin after simulations of the first, second, and third doses of vancomycin

Regimen (mg/kg) First
Second
Third
Cmin48(μg/ml) AUC0 to 48(μg/h per ml) Cmin96(μg/ml) AUC48 to 96(μg/h per ml) Cmin144(μg/ml) AUC96 to 144(μg/h per ml)
15 LD, 7.5 MD 8.7 ± 1.4 892 ± 182 8.9 ± 1.5 866 ± 164 9.0 ± 1.6 873 ± 163
15 LD, 15 MD 8.7 ± 1.4 892 ± 182 13.2 ± 2.2 1310 ± 253 15.6 ± 2.7 1530 ± 289
20 LD, 7.5 MD 11.7 ± 1.9 1190 ± 243 10.4 ± 1.8 1006 ± 188 9.7 ± 1.7 945 ± 175
20 LD, 10 MD 11.7 ± 1.9 1190 ± 243 11.8 ± 2.0 1160 ± 218 11.9 ± 2.1 1160 ± 217

Data are means ± SD.