Table 3.
Overall performance of eGFR in kidney donors: Pre- and postdonation values for MDRD, CKD-EPI, and CG/BSA in n = 253
| Parameter | Difference between mGFR and eGFR (ml/min per 1.73 m2) |
% Difference between mGFR and eGFR |
R2 | P30 (%) | ||
|---|---|---|---|---|---|---|
| Median (95% CI) | IQR (95% CI) | Median (95% CI) | IQR (95% CI) | |||
| Before donation | ||||||
| MDRD | 22 (20 to 25) | 20 (14 to 26) | 22 (20 to 24) | 17 (12 to 21) | 0.16 | 73 (68 to 79) |
| CKD-EPI | 14 (11 to 16) | 18 (14 to 22) | 13 (11 to 16) | 16 (13 to 21) | 0.20 | 89 (85 to 93) |
| CG/BSA | 10 (7 to 12) | 21 (16 to 29) | 10 (7 to 12) | 21 (16 to 28) | 0.14 | 90 (86 to 94) |
| After donation | ||||||
| MDRD | 15 (14 to 16)a | 12 (9 to 15) | 23 (21 to 25)a | 17 (12 to 21) | 0.31 | 71 (65 to 76) |
| CKD-EPI | 11 (9 to 11)a | 12 (10 to 16) | 16 (14 to 19)a | 20 (15 to 23) | 0.35 | 89 (85 to 93) |
| CG/BSA | 4 (2 to 5)a | 14 (11 to 18) | 6 (3 to 9)a | 22 (11 to 27) | 0.31 | 93 (90 to 96) |
Bias median mGFR − eGFR (ml/min per 1.73 m2; tested by paired Wilcoxon signed-ranks test). Precision: IQR of difference between mGFR and eGFR; R2 from regressing eGFR on mGFR. Accuracy: Percentage of eGFR within 30% of mGFR (tested by χ2).
a
P < 0.05 before versus after donation.