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. 2010 Dec 14;8(12):e1000561. doi: 10.1371/journal.pbio.1000561

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Huang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The KI67 positive cell counts in the dentate gyrus of the hippocampus 10 d after CD4, CD8, or CD4 and CD8 T cell depletion by antibody injection. Each group consisted of eight animals. (B) The KI67 positive cell counts in the hippocampus after 2 wk of reconstitution of TCRα knockout mice with CD4 or CD8 lymphocytes by intraperitoneal injection of 2×10⁷ cells/mouse. Each group consisted of six animals. Values shown are means ± SEM.