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. 2010 Dec 13;191(6):1049–1060. doi: 10.1083/jcb.201007028

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© 2010 Cabianca and Gabellini

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Figure 3. — SNPs and sequence variants at 4q35. 18 different 4q haplotypes have been described. FSHD patients carry D4Z4 deletions in 4qA161, 4qA159, and 4qA168 backgrounds. These genetic contexts represent a permissive condition for the disease rather than a cause given that asymptomatic carriers have been described. SSLP, simple sequence length polymorphism; TEL, telomere.