Table 2.
Gene-Based Scores that Summarize the Combined Evidence for Selection across Each UCP Gene.
Gene-Based Scorea (P valueb) |
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Gene | Method | Absolute Latitude |
Minimum Temperature |
Maximum Temperature |
Mean Temperature |
Precipitation Rate |
Solar Radiation |
Relative Humidity |
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UCP1 | SRC | 2.8 | (0.010) | 2.1 | (0.036) | 2.4 | (0.017) | 2.4 | (0.023) | 0.6 | (0.720) | 2.8 | (0.008) | 0.6 | (0.760) |
BLM | 1.3 | (0.228) | 0.6 | (0.766) | 0.8 | (0.562) | 0.7 | (0.649) | 0.8 | (0.583) | 1.7 | (0.105) | 0.7 | (0.698) | |
UCP2 | SRC | 0.8 | (0.636) | 0.6 | (0.791) | 0.7 | (0.724) | 0.6 | (0.782) | 0.7 | (0.646) | 0.8 | (0.601) | 0.9 | (0.455) |
BLM | 2.5 | (0.026) | 2.5 | (0.023) | 3.0 | (0.011) | 2.7 | (0.014) | 1.0 | (0.383) | 1.8 | (0.097) | 1.2 | (0.290) | |
UCP3 | SRC | 1.1 | (0.371) | 2.2 | (0.015) | 1.7 | (0.050) | 2.0 | (0.026) | 1.0 | (0.432) | 0.8 | (0.616) | 0.7 | (0.718) |
BLM | 3.0 | (0.003) | 3.3 | (0.001) | 3.1 | (0.002) | 3.3 | (0.002) | 1.5 | (0.115) | 2.4 | (0.017) | 1.0 | (0.460) |
The gene-based score is the average of the negative log-transformed P values across all SNPs in a gene.
P values are calculated by comparing the score for an UCP region to the scores for 10,000 randomly chosen genic regions with the same number of SNPs.