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. 2010 Nov 29;4:15. doi: 10.1186/1754-1611-4-15

Table 1.

Stimuli-sensitive drug delivery.

Stimulus Carrier type Payload Reference
pH PPADK Dexamethasone [45]

DMAEMA/HEMA Paclitaxel [3]

PC/DAP liposomes siRNA [51]

Temperature PNIPAm/PLGA Paclitaxel [36]

MPPC/DPPC/HSPC/DSPEC-PEG-2000 Doxorubicin [54]

FA/PDMA/PNIPAm Dipyridamole [57]

Light Cu chlorophyllin/PNIPAm None reported [60]

Quinone-methide Nile Red [63]

Au/meso porous silica Paclitaxel [61]

Ultrasound Pluronic P105/N,N-diethylacrylamide Doxorubicin [66]

DPPC:DPPE-PEG2000 liposomes Calcein [67]

Glucose poly(methacrylic acid-g-ethylene glycol) with glucose oxidase, PNIPAm with phenylboronic acid Insulin [69-72]

PNIPAm or carboxymethyl dextran with con. A None reported [73,74]

Enzyme PEG diacrylate/human neutrophil elastase-sensitive peptide None reported [75]

Fibrin/β-nerve growth factor fusion proteins β-nerve growth factor [76]

sPLA2-degradable retinoid lipid pro-drug Retinoid lipid pro-drug [77]

Magnetic Magnetite Squalenoyl gemcitabine (SQdFdC) [78]

Poly[aniline-co-N-(1-one-butyric acid)] aniline (SPAnH)/iron oxide Epirubicin [79]

Polylactide/nanocrystalline magnetite Paclitaxel [80]

Egg-PC/maghemite/PAH/PSS Calcein [81]