Table 3.
13 Modules in gene coexpression network in Figure 2 with their enriched pathways.
Module | Module color | Pathway category | Name | P-value |
---|---|---|---|---|
1 | Purple | Cell signaling | Ion channel and phorbal esters signaling | 8.60E-03 |
2 | Wind stawberry |
Apoptosis | Apoptotic DNA fragmentation and tissue homeostasis | 3.52E-02 |
Cell cycle regulation | Activation of Src by protein-tyrosine phosphatase alpha | 4.23E-02 | ||
Cell cycle regulation | AKAP95 role in mitosis and chromosome dynamics | 4.98E-02 | ||
Cell cycle regulation | Sonic Hedgehog (SHH) Receptor Ptc1 regulates cell cycle | 4.23E-02 | ||
3 | Forest green | Translation | Ribosome | 3.32E-09 |
4 | Teal blue | Metabolism of cofactors and vitamins | One carbon pool by folate | 4.72E-02 |
5 | Black | Cell signaling | Ca++/Calmodulin-dependent protein kinase Activation | 3.59E-03 |
6 | Green yellow |
Immunology | Cells and molecules involved in local acute inflammatory response | 4.68E-02 |
7 | Yellow | Cell growth and death | Cell cycle | 2.62E-02 |
8 | Orange | Immunology | Classical complement | 2.85E-02 |
9 | Lavender | Cell signaling | IFN alpha signaling | 1.03E-02 |
10 | Blue | Cell activation | Th1/Th2 differentiation | 3.79E-02 |
11 | Olive green | Metabolism | Electron transport reaction in mitochondria | 1.31E-02 |
Energy metabolism | Oxidative phosphorylation | 9.00E-03 | ||
Neuro-degenerative diseases | Parkinson's disease | 8.67E-03 | ||
12 | Maroon | Translation | Ribosome | 1.13E-03 |
13 | Red | Metabolism/Neuroscience | Vitamin C in the brain | 9.11E-03 |
Cell activation | Angiotensin-converting enzyme 2 regulates heart function | 1.27E-02 | ||
Metabolism | Intrinsic prothrombin activation | 3.83E-02 | ||
Metabolism | Platelet amyloid precursor protein | 1.47E-02 | ||
Hematopoiesis | Regulators of bone mineralization | 2.58E-03 |