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. 2010 Nov 10;10:91. doi: 10.1186/1471-244X-10-91

Table 4.

Self-reported medication side effects of patients (N = 423)* according to treatment type

FGA1 SGA2


men women men women




Parkinson symptoms 17% 15.6% 3.8% 11.6%
dyskinetic/dystonic symptoms 35.8% 31.3% 9.4% 9.7%
akathisia 22.6% 12.5% 6% 6.8%
hyperprolactinaemia - - - 1.9%
hormonal dysfunctions (gynecomastia, absence/changes of menorrhea) - 9.4% - 5.8%
sexual dysfunction 7.5% - 10.3% -
vertigo (incl. hypotonia) 5.7% 12.5% 5.1% 8.7%
weight gain 9.4% 18.7% 38.3% 39.8%
diabetes mellitus - - 0.4% -
sialorrhea ('drooling') - - 20.4% 6.8%
skin abnormalities, loss of hair 1.9% - 1.7% 5.8%
gastrointestinal symptoms 1.9% 6.3% 5.9% 7.8%
hyperhidrosis - - 2.6% -
psychological symptoms (loss of concentration, no drive, tiredness) 33.9% 28.1% 44.2% 31.1%
cardiovascular symptoms (tachycardia, hypertension) - - 1.3% 1.9%
impaired vision - - 1.7% 3.9%
dry mouth 5.7% 9.4% 5.1% 4.9%
urinary retention - 3.1% 1.3% -
number of patients who reported side effects 53 32 235 103

1FGA - first generation antipsychotics, typical antipsychotics

2SGA - second generation antipsychotics, atypical antipsychotics

*Only N = 423 patients (out of 1012 patients who were on antipsychotic medication) reported side effects (see text for details).