Table 2.
Hemodynamic tolerability of CRRT vs SLED
| CRRT (n = 86) | SLED (n = 39) | p-value | |
|---|---|---|---|
| MAP prior to treatment session (mmHg) | 74.1 ± 10.0 | 76.4 ± 13.1 | 0.34 |
| Vasopressor requirement prior to RRT session (%) | 62 (72.1) | 19 (48.7) | 0.01 |
| Volume ultrafiltered per session (mL) | 1823 ± 1464 | 1915 ± 1302 | 0.74 |
| Sessions associated with > 20% reduction in MAP (%) | 16 (18.6) | 15 (38.5) | 0.02 |
| Sessions with vasopressor escalation (%)a |
34 (39.5) | 10 (25.6) | 0.13 |
| Unstable sessionsb (%) | 43 (50.0) | 22 (56.4) | 0.51 |
Continuous variables are presented as mean ± SD. Categorical variables are presented as number of sessions (%).
SLED = sustained low efficiency dialysis
CRRT = continuous renal replacement therapy
MAP = mean arterial pressure
aIncludes any increase in pressor dosage, as well as initiation of pressors
bDefined as a treatment associated with a > 20% intra-treatment reduction in MAP or a treatment on which an escalation in pressor requirement occurred