Table 5.

Randomized controlled trials comparing the hemodynamic tolerability of CRRT and IHD

	CRRT (n)	IHD (n)	Definition of Hemodynamic Tolerability	Outcome
Misset et al a[4]	27	27	Amplitude of MAP change (lowest recorded every hour to highest recorded), and episodes of MAP reduction by > 10 mmHg	No significant difference (p = 0.72 and 0.73, respectively)
Augustine et al [6]	40	40	Difference between mean MAP in 12 hours prior to RRT and during RRT	Significant drop in MAP during IHD (p = 0.04)
Uehlinger et al [7]	70	55	Number of hypotensive events (MAP < 65) during RRT	No significant difference (p = 0.36)
Vinsonneau et al [8]	175	184	Number of hypotensive events (SBP < 80, or drop of greater than 50 mmHg) during RRT	No significant difference (p = 0.47)

^aA cross-over study with a 24-hour wash-out period

MAP, mean arterial pressure; SBP, systolic blood pressure