Table 4.
First author/date of study | n | Drug | Treatment duration (months) | Transaminase reduction | Histologie improvement |
Laurin et al. (1996) | 16 | Clofibrate | 12 | No | No |
Basaranoglu et al. (1999) | 46 | Gemfibrozil | 1 | Yes | No data |
Saibara et al. (1999) | 2 | Bezafibrate | 10 | No data | Yes; steatosis |
Horlander et al. (2001) | 7 | Atorvastatin | 12 | Yes | Yes; only inflammation improved |
Kiyici et al. (2003) | 27 | Atorvastatin | 6 | Yes | Yes; steatosis |
Rallidis et al. (2004) | 5 | Pravastatin | 6 | Yes | Yes; steatosis and inflammation better |
Antonopoulos et al. (2006) | 23 | Rosuvastatin | 8 | Yes | No data |
Merat et al. (2007) | 10 | Probucol | 12 | Yes | Yes; steatosis and inflammation better |
Fernandez-Miranda et al. (2008) | 16 | Fenofibrate | 12 | Yes | Yes; reduced hepatocellular ballooning |