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. 2008 Nov;1(3):173–189. doi: 10.1177/1756283X08096951

Table 4.

Lipid-Lowering agents in the treatment of nonalcoholic fatty liver disease.

First author/date of study n Drug Treatment duration (months) Transaminase reduction Histologie improvement
Laurin et al. (1996) 16 Clofibrate 12 No No
Basaranoglu et al. (1999) 46 Gemfibrozil 1 Yes No data
Saibara et al. (1999) 2 Bezafibrate 10 No data Yes; steatosis
Horlander et al. (2001) 7 Atorvastatin 12 Yes Yes; only inflammation improved
Kiyici et al. (2003) 27 Atorvastatin 6 Yes Yes; steatosis
Rallidis et al. (2004) 5 Pravastatin 6 Yes Yes; steatosis and inflammation better
Antonopoulos et al. (2006) 23 Rosuvastatin 8 Yes No data
Merat et al. (2007) 10 Probucol 12 Yes Yes; steatosis and inflammation better
Fernandez-Miranda et al. (2008) 16 Fenofibrate 12 Yes Yes; reduced hepatocellular ballooning