Table 2.
Acute management | Prophylactic management |
Acetaminophen 1000mg | Amitriptyline10-75mg/day |
Ibuprofen 200-400mg | Mirtazapine 30mg/day |
Naproxen sodium 375-550mg | |
Ketoprofen 25-50mg | |
Diclofenac potassium 50-100mg |
Physicians should be aware of the risk of developing medication-overuse headache as a result of frequent and excessive use of analgesics in acute therapy. Dosages in prophylactic management with amitriptyLine are increased until efficacy or side effects are reported.