Tab. 5.
Composition of vinpocetine sublingual tablets.
| Formulationa | Vinpocetine Kneaded Solid System (mg)b | Camphor (%) | Menthol (%) | Ac-Di-Sol (%) | Mannitol up to (mg) |
|---|---|---|---|---|---|
| F1 | 41.66 | 200 | |||
| F2 | 41.66 | 10 | 200 | ||
| F3 | 41.66 | 20 | 200 | ||
| F4 | 41.66 | 10 | 200 | ||
| F5 | 41.66 | 20 | 200 | ||
| F6 | 41.66 | 5 | 200 | ||
| F7 | 41.66 | 10 | 5 | 200 | |
| F8 | 41.66 | 20 | 5 | 200 | |
| F9 | 41.66 | 10 | 5 | 200 | |
| F10 | 41.66 | 20 | 5 | 200 |
a
All batches contained 2% Kollidon CL as a bioadhesive agent, and 0.25% magnesium stearate as a lubricant.
b
Vinpocetine: βCD: tartaric acid kneaded solid system in 1:2:2 molar ratios equivalent to 5 mg vinpocetine.