Table 1. Clinical characteristics of study population according to genotype at the rs12255372.
| All | GG | GT | TT | ||
|---|---|---|---|---|---|
| (n=250) | (n=81) | (n=133) | (n=36) | P | |
| Age (years) | 28.1±3.2 | 27.2±3.4 | 27.6±3.3 | 28.2±2.7 | 0.737 |
| Gender | 135F/115M | 42F/39M | 73F/60M | 20F/16M | 0.573 |
| BMI (kg/m2) | 23.2±3.3 | 22.7±3.3 | 23.9±3.5 | 24.0±2.8 | 0.395 |
| WHR | 0.77±0.12 | 0.76±0.10 | 0.80±0.11 | 0.78±0.06 | 0.196 |
| FPG (mmol/l) | 5.1±0.7 | 4.8±0.4 | 4.7±0.4 | 5.3±0.4§ | 0.002 |
| Total cholesterol (mg/dl) | 158±17 | 161±17 | 156±17 | 158±21 | 0.567 |
| HDL cholesterol (mg/dl) | 48±2 | 48±2 | 47±3 | 48±2 | 0.455 |
| Triglycerides (mg/dl) | 87±21 | 87±14 | 91±23 | 98±17 | 0.321 |
| HR (beats/min) | 71±5 | 71±6 | 72±7 | 73±6 | 0.391 |
| SBP (mm Hg) | 113±9 | 114±10 | 111±10 | 115±10 | 0.550 |
| DBP (mm Hg) | 72±7 | 73±8 | 71±8 | 74±7 | 0.500 |
Data are means±SD.
Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HR, heart rate; SBP, systolic blood pressure; WHR, waist/hip ratio.
P values between groups, §P=0.01 TT vs GT; P=0.02 TT vs GG by one-way ANOVA followed by Bonferroni multiple testing correction.