Table 1. Demographics of the family groups.
| Index patient (IP) | Relative 1 | Relative 2 | |
|---|---|---|---|
| Family 1 | |||
| Name (age) | Angela (55) | Zoe (28) | Ruth (50) |
| Relationship to IP | Daughter | Sister | |
| Mutation status | BRCA1 | Untested | Untested |
| Cancer diagnosis | Ovarian | — | Breast |
| Family 2 | |||
| Name (age) | Sarah (38) | Laura (50) | Katie (38) |
| Relationship to IP | Sister | Niece | |
| Mutation status | BRCA2 | BRCA2 | Negative |
| Cancer diagnosis | Breast | — | — |
| Family 3 | |||
| Name (age) | Margaret (60) | Anna (41) | Jill (55) |
| Relationship to IP | Daughter | Cousin | |
| Mutation status | BRCA2 | BRCA2 | Negative |
| Cancer diagnosis | Breast × 2 | — | Ovarian |
| Family 4 | |||
| Name (age) | Rose (71) | Joanna (33) | Lucy (34) |
| Relationship to IP | Daughter | Niece | |
| Mutation status | BRCA1 | Awaiting result | Untested |
| Cancer diagnosis | Breast and ovarian | — | — |
| Family 5 | |||
| Name (age) | Phillipa (64) | Thomas (39) | Edward (35) |
| Relationship to IP | Son | Son | |
| Mutation status | BRCA2 | Negative | Negative |
| Cancer diagnosis | Breast | — | — |
| Family 6 | |||
| Name (age) | Claire (64) | Helen (65) | John (60) |
| Relationship to IP | Sister | Brother | |
| Mutation status | BRCA1 | BRCA1 | Awaiting result |
| Cancer diagnosis | Breast and ovarian | Mouth | — |
| Family 7 | |||
| Name (age) | Joan (63) | James (37) | Simon (35) |
| Relationship to IP | Son | Son | |
| Mutation status | BRCA2 | Untested | Untested |
| Cancer diagnosis | Ovarian | — | — |
| Family 8 | |||
| Name (age) | Alice (43) | Danielle (20) | Judy (37) |
| Relationship to IP | Daughter | Cousin | |
| Mutation status | BRCA1 | Untested | Untested |
| Cancer diagnosis | Breast | — | — |
| Family 9 | |||
| Name (age) | Elizabeth (34) | Teresa (22) | Marie (21) |
| Relationship to IP | Sister | Sister | |
| Mutation status | BRCA1 | Untested | Untested |
| Cancer diagnosis | Breast | — | — |
| Family 10 | |||
| Name (age) | Rachel (63) | Tara (26) | Sophie (29) |
| Relationship to IP | Daughter | Daughter | |
| Mutation status | BRCA1 | Untested | Untested |
| Cancer diagnosis | Breast and ovarian | — | — |