Table 3.
Multivariate analysisa of potential risk factors related to development of atopic and non-atopic wheezing and atopy in 1,309 children
| Potential risk factors | Non-atopic wheezers (vs. non-atopic non-wheezers)b | Atopic wheezers (vs. atopic non-wheezers)b | Atopic (vs. non-atopics)c |
|---|---|---|---|
| OR (95%CI) | OR (95%CI) | OR (95%CI) | |
| Social/familial factors | |||
| Mother education (reference group: High) | |||
| Medium | 1.30 (0.88 to 1.93) | 0.94 (0.60 to 1.46) | 0.95 (0.73 to 1.24) |
| Low(elementary or illiterate) | 1.49 (0.93 to 2.38) | 1.24 (0.73 to 2.11) | 1.01 (0.73 to 1.39) |
| Parental Asthma (reference: no parental asthma) | 1.91 (1.25 to 2.92) | 2.64 (1.48 to 4.73) | 0.73 (0.51 to 1.03) |
| Dirt and Infections | |||
| Infrequent household cleaning (reference: frequent cleaning) | 2.49 (1.27 to 4.90) | 2.27 (0.82 to 6.29) | 0.72 (0.39 to 1.31) |
| Rodents in home (reference: no rodents) | 1.68 (1.21 to 2.34) | 0.79 (0.54 to 1.15) | 0.90 (0.71 to 1.13) |
| Having attended day care (reference: no attendance) | 1.52 (1.01 to 2.29) | 0.83 (0.49 to 1.41) | 0.92 (0.67 to 1.26) |
| T. gondii seropositivity (reference: negative) | 1.23 (0.82 to 1.84) | 1.51 (0.90 to 2.54) | 0.68 (0.50 to 0.93) |
| A. lumbricoides-specific IgG4 (reference: negative) | 1.25 (0.79 to 1.97) | 1.20 (0.75 to 1.92) | 1.73 (1.27 to 2.34) |
| Respiratory symptoms (reference: no symptoms) | |||
| for 1-7 days | 1.54 (1.01 to 2.36) | 1.54 (0.92 to 2.59) | 0.89 (0.65 to 1.21) |
| for ≥8 days | 4.87 (2.26 to 9.76) | 2.27 (0.97 to 5.38) | 1.31 (0.74 to 2.31) |
| Diarrhea (reference: no diarrhoea) | |||
| for 1-7 days | 1.09 (0.67 to 1.80) | 1.02 (0.58 to 1.81) | 1.18 (0.85 to 1.64) |
| for ≥8 days | 1.59 (0.95 to 2.66) | 1.29 (0.70 to 2.40) | 1.03 (0.72 to 1.49) |
a controlled by age and sex, and adjusted for all factors included in the table.
b multinomial logistic regression
c ordinary logistic regression