Figure 4.

Hazard rate estimates for distant metastasis by metastatic site in 1528 ERP tumours (A) and in 391 ERN tumours (B) from patients undergoing conservative surgery (quadrantectomy or tumourectomy) plus RT. The similarity of recurrence dynamics provides evidence that recurrence timing is generated by factors influencing the metastatic development, regardless of the seeded organ. Vertical lines represent point-wise confidence interval for the model estimated hazards, according to standard asymptotic theory.