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. 2010 Dec 16;6(12):e1001249. doi: 10.1371/journal.pgen.1001249

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Barreiro et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Venn-diagram showing the number of genes whose expression levels were altered following stimulation with LPS in humans, chimpanzees and rhesus macaques at any time point (see Figure S4 for data from specific time points). (B) Gene ontology (GO) enrichment analysis using the subset of genes that responded to the treatment in all three species. GO terms related to immunity processes are plotted (see Table S2 for results including all GO terms). (C) KEGG pathway enrichment analysis for genes that responded to the treatment in all three species. (D) Transcription factor binding site enrichment analysis in the promoters of genes that responded to the treatment in all three species (see Table S3 for complete results).