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. 2010 Nov 22;107(50):21665–21670. doi: 10.1073/pnas.1014376107

Fig. 4.

Fig. 4.

2D-PAGE proteomic analysis of immunoprecipitated (IP) GCase and Western blot analysis of GCase and immunoprecipitated TCP1 from normal and GD fibroblasts. (A) Analysis of binding partners from immunoprecipitated GCase in normal and types 1, 2, and 3 GD cells (Upper, left to right). Arrows indicate TCP1. (Lower) Western blot using GCase antibody on normal and types 1, 2, and 3 GD cells with GCase-immunoprecipitated proteins. (B Upper) Western blot using TCP1 antibody on GCase- immunoprecipitated proteins from GD and normal fibroblasts. (Lower) Western blot using GCase antibody on the same proteins. (C) Western blot from TCP1-immunoprecipitated proteins. (Upper) Western blot using GCase antibody on TCP1-immunoprecipitated proteins from GD and normal fibroblasts. (Lower) Western blot using TCP1 antibody on same proteins.