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Effect of F185 mutations on integrin α4β7-mediated cell migration. (A) Wound-healing migration of CHO-K1 stable cells. Representative images are from Movies S1 and S2 at the indicated time. Bar, 50 μm. (B) Single cell random migration of CHO-K1 stable cells. Migration tracks of ten randomly picked cells are shown. (C) Serum-induced transwell migration. Cells migrating to the lower chamber were counted. Error bars are ± s.d. (n = 3), **: P < 0.01.
