TABLE 2.

COMPARISON OF INTRA-DAY AND INTERDAY PRECISION AND ACCURACY

Amount	HPLC method			UV spectrophotometric
	Mean area	SD	RSD%	Mean area	SD	RSD%
Within day precision
20	933.55	5.92	0.634	0.205	0.001	0.357
40	1576.12	1.09	0.069	0.229	0.001	0.069
60	2350.64	9.47	0.398	0.288	0.001	0.173
(Acceptance Criteria RSD<2)
Between day precision
20	923.843	5.591	0.601	0.204	0.001	0.283
40	1585.137	11.175	0.704	0.231	0.003	1.5
60	2355.138	12.788	0.542	0.286	0.004	1.415
(Acceptance Criteria RSD<3)

Comparision of intra-day and inter-day precision and accuracy for the determination of zonisamide 100 mg by HPLC and UV-spectrophotometric methods