TABLE 2.
HEPATOPROTECTIVE ACTIVITY OF MICROSPHERE 2 FORMULATION
| Groups | Body weights on day 9 (g) | SGOT (u/1) | SGPT (u/1) | Histo1ogy |
|---|---|---|---|---|
| Control | 202±15 | 18.66±4.2 | 8.85±3.2 | Normal liver |
| CCl4 treated | 150±12 | 53.60±6.8 | 37.13±2.4 | Massive necrosis and hepatitis of liver parenchyma |
| CCl4 treated+IV 4-chlorocurcumin solution | 190±18 | 42.10±1.5 | 25.7±1.8 | Normal liver |
| CCl4 treated+microsphere 2 | 185±15 | 32.94±3.8 | 18±1.5 | Normal liver |
| Control+PEG solution | 208±8 | 18.23±2.5 | 9.2±2.5 | Normal liver |
| Control+Placebo microspheres | 195±12 | 20.4±4.5 | 10.4±2.5 | Normal liver |