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. 2010 Dec 15;24(24):2754–2759. doi: 10.1101/gad.1950610

Figure 2.

Figure 2.

Expression of miR-143/145 inhibits transformation and tumorigenesis in pancreatic cancer cells. (A) Anchorage-independent growth of retrovirally infected cell lines (average of three independent experiments shown). Error bars for this and subsequent panels represent standard deviations. (B) Tumorigenesis assays with retrovirally infected MiaPaCa2 cells. Images depict a representative animal injected in each flank with cells infected with empty virus or miR-143/145 virus. The graph shows the average tumor volume (n = 5 mice per cell line). (C) Anchorage-independent growth of retrovirally infected cell lines expressing either miR-143 or miR-145. (D) Tumorigenesis assays with MiaPaCa2 cells infected with empty virus or virus expressing miR-143 or miR-145 (n = 5 mice per cell line).