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Phase contrast photomicrographs of cultured adult rat DRG neurons. A. without oxaliplatin; B. after 48 hour treatment with 5 μg/ml oxaliplatin, C. 20 μg/ml oxaliplatin and D. 50 μg/ml oxaliplatin, showing a dose-related loss of neurite integrity, loss of cell bodies, and accumulation of cell debris. Bar = 50 μm.
