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Lens-specific Brg1 targeting gives rise to a variety of ocular deficiencies. The cKO mutants were compared with Brg1flox/flox littermates at postnatal day 1 (A-C) and postnatal day 7 (D-I). The mutant mice displayed ocular defects with various severities, including failure of cornea-eyelid separation (black arrows in B and C) or iris separation (E, I and H), aberrant lens and retina (B, C, E, F, and H) and even an absence of lens structure (I). Scale bar, 100 μm.
