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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Expert Opin Biol Ther. 2010 Aug;10(8):1227–1239. doi: 10.1517/14712598.2010.495218

Figure 5. Sox2 induced the loss of pigmentation and the presence of RA4+ cells in the RPE layer of chick eyes.

Figure 5

A: Cross-section of a control E15 retina infected with RCAS-GFP. B: Cross-section of an experimental E15 retina infected with RCAS-Sox2. C: RA4 immunostaining of an experimental retina. D: Higher magnification of C. Asterisks mark the RPE. Arrows point to RA4+ axons of retinal ganglion cells. Arrowheads point to RA4+ cells in the RPE layer.

AX: Axons of retinal ganglion cells; RGC: Retinal ganglion cells; RPE: Retinal pigment epithelium.