Table 1.

Substrate scope for three-component coupling.

Product[a]	R	Yield [%]
8a	Ph	72[b]
8b	4-Cl-C6H4	70[b]
8c	2-thienyl	65[b]
8d	2-furyl	64[b]
8e	(E)-CH=CH-C6H5	66[b]
8 f	H	57[c]
8g	n-pentyl	58[b]
8h	iPr	53[c]
8i	tBu	36[c]

^[a]Reagents: Silyl glyoxylate (1.5 equiv), nitroalkene (1 equiv), CH₂= CHMgBr (1.5 equiv), [4]₀=0.1m in C₇H₈;

^[b]Yield of isolated product.

^[c]Yields were determined by ¹H NMR spectroscopy of crude product compared to an internal standard of mesitylene.