TABLE 1.
Proteins identified as suppressors of the NG toxicity
Protein | Inducer useda | Cellular location | Function |
---|---|---|---|
PgsAb | IPTG/arabinose | Inner membrane | Biosynthesis of acidic phospholipids |
MdfAc | IPTG | Inner membrane | Multidrug transporter |
SetAc | IPTG | Inner membrane | Sugar efflux transporter |
YdeAc | IPTG/arabinose | Inner membrane | Sugar efflux transporter |
a The screening was performed in two different systems, in which the NG was expressed under different inducible promoter (tac and ara promoter) utilizing different inducers (IPTG or arabinose, respectively).
b Protein was identified.
c Protein was uncharacterized.