FIGURE 6.

hAGT expression is increased in the liver and kidney of double transgenic mice containing −6A haplotype of the hAGT gene as compared with −6G haplotype. A, RNA from the liver and kidney of transgenic mice containing either −6A or −6G haplotype of the hAGT gene was analyzed by quantitative RT-PCR. B, immunohistochemistry of hAGT in sections from the liver of transgenic mice containing −6A or −6G haplotype of the hAGT gene. C, Western blot analysis of hAGT in the liver of transgenic mice containing −6A or −6G haplotype of the hAGT gene. D, quantitation of hAGT protein in livers of transgenic mice containing −6A or −6G haplotype of the hAGT gene as determined by Western blot. Quantitation was performed after normalization with β-actin. Error bars, S.E.