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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Clin Endocrinol (Oxf). 2009 Oct 22;72(6):744–751. doi: 10.1111/j.1365-2265.2009.03725.x

Table 3.

Correlation coefficient between microRNA and gene target expression The previous analysis indentified ten potential microRNA-gene target pairs. For each microRNA and gene target we performed real-time PCR analysis in order to identify their expression levels in MMAD tissues. Due to the fact that microRNAs are negative regulators of gene expression, we were interested in the microRNA-gene target pairs with very high inversely correlated expression levels. In the table above we present the correlation coefficient between microRNA and gene target expression levels, starting from the most significant. The most significant inverse correlation was between miR-200b and MATR3 expression levels. We have identified miR-200b as the most highly down-regulated (-9.36 fold) microRNA in MMAD (according to microRNA microarray data) while MATR3 was highly up-regulated (5.56 fold) in MMAD tissues (cDNA microarray data from Bourdeau et al study).

microRNA Gene Target Correlation coefficient
miR-200b MATR3 -0.984
miR-203 KRT1 -0.877
miR-196a CPE -0.813
miR-196b CPE -0.807
miR-203 CCNG1 -0.673
miR-200c MATR3 -0.554
miR-200b PUM2 -0.534
miR-200c PUM2 -0.512
miR-148a TXNIP -0.451
miR-146b PSMC6 -0.404