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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Cancer Res. 2010 Nov 23;70(23):10002–10011. doi: 10.1158/0008-5472.CAN-10-2606

Figure 5.

Figure 5

Cx43 localizes to the plasma membrane after LY294002 or LY303511 treatment. (A) Representative immunoblot analysis from three independent experiments of Cx43 in C8161.9 and MDA-MB-231 6 hr post treatment with 10μM LY294002 and LY303511. (B) Quantification of Cx43 immunoblot analyses (n=3) [** = p<0.01]. (C) Exposure of C8161.9 or MDA-MB-231 cells to LY294002 (10 μM) or LY303511 (10 μM) for 6 hr resulted in substantially more plasma membrane localization of Cx43 than untreated (NT) cells. Arrows highlight Cx43 plaques between cells.