Fig. 2.
Structurally similar domains and their structural elements. Some structurally similar proteins contain nearly identical secondary structure elements in similar orientations. Hemoglobin, chain A (PDB:2MHB, chain A) and myoglobin (1A6N) are two such members of the globin fold. Chemotaxis protein Y (PDB:3CHY), Histamine N-methyltransferase (PDB:2AOT) and Catechol O-methyltransferase (1VID) have a conserved structural core surrounded by some non-conserved regions.