Table 5.

Predictors of overall survival in neuroendocrine tumour liver metastases

Variables	Median OS, months	P-value	Multivariate RR (95%CI), P-value
Grade
High	6	<0.001	9.5 (3.0–29.9), <0.001
Intermediate	48		5.9 (2.0–17.2), 0.001a
Low	NR
Blood lossb
High	61	0.96	–
Low	67
Margins
Positive	63	0.68	–
Negative	61
Largest tumour size
≥8.5 cm	61	0.44	–
<8.5 cm	67
Liver tumour number
≥2	48	0.99
<2	63
CD3
High	61	0.29	–
Low	108
CD8
High	47	0.21	–
Low	67
CD4
High	48	0.36	–
Low	103
FoxP3
High	47	0.029	0.08
Low	108

^aSeparate multivariate model for intermediate or high grade vs. low grade

^bMedian blood loss volume used a cut-off point

OS, overall survival; RR, relative risk; 95% CI, 95% confidence interval; NR, not reported