Apolipoproteins protect from inflammation. Apolipoprotein (Apo) A-I inhibits T-cell/monocyte interactions, thus blocking the production of IL-1 and TNF and reducing inflammation. CRP, C-reactive protein; SAA, serum amyloid A; HDL, high-density lipoprotein; sTL, stimulated T lymphocyte; MΦ, macrophages. Figure kindly provided by Prof. Jean-Michel Dayer (Geneva, Switzerland).