Table 1.
Reference values for antibodies tested and their values in Crohn's disease
| Antibody | Positive cutoff reference value | Median value in CD, Range | Percent positive in CD |
|---|---|---|---|
| ASCA IgG | 20 EU | 26.9, 0-415.2 | 38.1% |
| ASCA IgA | 40 EU | 12.5, 0-164 | 38.1% |
| Anti-I2 | 30 EU | 18.9, 0-324.1 | 46.8% |
| Anti-OmpC | 23 EU | 15.2, 0-296.4 | 31.7% |
| Anti-CBir1 | 30 EU | 26.1, 0-279.7 | 49% |
| ANCA | 30 EU | 1.4-277.7* | 74%* |
The positive cutoff value is two standard deviations above the mean value in healthy controls. *These values apply to ulcerative colitis as opposed to crohn's disease.
ANCA = antineutrophil cytoplasmic antibodies; anti-CBir1 = anti-flagellin; anti-OmpC = anti-Escherichia coli outer membrane porin C; ASCA = Anti-Saccharomyces cerevisiae antibody; CD = Crohn's disease; EU = ELISA units.