FIG. 3.

Correlation between increased AHR binding and altered gene expression. (A) Scatter plot of all 78 genes comparing log₂ fold-change (FC) AHR binding by ChIP-on-chip versus log₂ fold-change of gene expression changes at 8 h. (B) Scatter plot of all 78 genes comparing log₂ fold-change AHR binding by ChIP-on-chip versus log₂ fold-change of gene expression changes at 12 h. (C) Scatter plot of gene subset showing increased AHR promoter binding comparing log₂ fold-change AHR binding by ChIP-on-chip versus log₂ fold-change of gene expression changes at 8 h. (D) Scatter plot of gene subset showing increased AHR promoter binding comparing log₂ fold-change AHR binding by ChIP-on-chip versus log₂ fold-change of gene expression changes at 12 h. The correlation coefficient (r) and associated p value are shown for each plot. The CYP1A1 gene was removed from all graphs for better visualization of the data points.