Table 5.
Model 3, adjusted risks for metabolic syndrome (MetS) calculated using each MetS component and their combinations as potential risk factors
| Baseline MetS components and combinations* | Adjusted-OR** | 95%CI | Overall (N = 1384) P |
SI† | 95%CI |
|---|---|---|---|---|---|
| Adults having single MetS component at baseline | NA‡ | - | - | - | - |
| COB alone | 9.1 | 2.8 - 29.9 | <0.01 | one risk alone | - |
| Hyper-TG alone | 3.4 | 1.5 - 7.7 | <0.01 | one risk alone | - |
| Hyper-GL alone | 3.0 | 1.5 - 6.0 | <0.01 | one risk alone | - |
| Low-HDL alone | 2.9 | 1.4 - 5.8 | <0.01 | one risk alone | - |
| HBP alone | 1.4 | 0.6 - 3.4 | 0.44 | one risk alone | - |
| Adults having two MetS components at baseline | NA | ||||
| COB-plus-Hyper-TG | 59.6 | 5.8 - 611.5 | <0.01 | 7.6 | 0.8 - 74.5 |
| COB-plus-Low-HDL | 24.6 | 7.7 - 78.2 | <0.01 | 2.8 | 0.8 - 9.2 |
| COB-plus-HBP | 14.5 | 3.6 - 59.1 | <0.01 | 2.0 | 0.5 - 8.5 |
| HBP-plus-Low-HDL | 11.7 | 5.1 - 27.0 | <0.01 | 4.7 | 2.1 - 10.9 |
| HBP-plus-Hyper-GL | 7.9 | 3.5 - 18.1 | <0.01 | 2.7 | 1.2 - 6.4 |
| COB-plus-Hyper-GL | 6.7 | 1.2 - 38.7 | <0.05 | 0.8 | 0.1 - 5.2 |
| HBP-plus-Hyper-TG | 5.8 | 2.2 - 15.4 | <0.01 | 1.6 | 0.6 - 4.3 |
| Low-HDL-plus-Hyper-TG | 5.7 | 2.7 - 12.3 | <0.01 | 1.6 | 0.7 - 3.3 |
| Hyper-GL-plus-Hyper-TG | 4.1 | 1.5 - 11.1 | <0.01 | 1.6 | 0.6 - 4.4 |
| Hyper-GL-plus-Low-HDL | 3.9 | 1.6 - 9.8 | <0.01 | 1.1 | 0.4 - 2.9 |
* Abbreviations: Hyper-GL, hyperglycemia; Low-HDL, Low-HDL cholesterolemia; HBP, high blood pressure; Hyper-TG, hypertriglyceridemia; COB, central obesity.;.
** Adjusted variables were age and categorical variables including gender, smoking, diet habits, drinking, exercise status, liver enzymes, sonographic fatty liver, hepatovirus infections, hyperinsulinemia and hyperuricemia.
† SI, synergistic index, SI value exceeding 1.0 indicates the presence of synergistic interaction.
‡ NA: Not analyzed in this model, analyzed and shown in Table 4, Model 2.
SI and 95%CI in bold are considered to be statistically significant.