Table 1. Induced genes in exosomes released under oxidative stress.
| Gene symbol/Gene name | Mean signal norm exo | Mean signal oxi exo | Fold change | p-value |
| [Vsig1] V-set and immunoglobulin domain containing 1 | 200 | 663 | 3.3 | 1.66E-03 |
| [Top1] topoisomerase (DNA) I | 540 | 1402 | 2.6 | 4.63E-02 |
| [Ccbp2] chemokine binding protein 2 | 356 | 897 | 2.5 | 3.32E-02 |
| [0610010K06Rik] RIKEN cDNA 0610010K06 gene | 383 | 966 | 2.5 | 1.32E-02 |
| [Krit1] KRIT1, ankyrin repeat containing | 325 | 811 | 2.5 | 2.41E-02 |
| [D230019N24Rik] RIKEN cDNA D230019N24 gene | 426 | 1015 | 2.4 | 5.42E-03 |
| [Amy2a1] amylase 2a1, pancreatic | 349 | 827 | 2.4 | 7.77E-04 |
| [Lba1] lupus brain antigen 1 | 532 | 1230 | 2.3 | 3.92E-02 |
| [Zfp385c] zinc finger protein 385C | 585 | 1349 | 2.3 | 1.73E-02 |
| [2700057C20Rik] RIKEN cDNA 2700057C20 gene | 528 | 1213 | 2.3 | 2.52E-03 |
| [Ptar1] protein prenyltransferase alpha subunit repeat containing 1 | 688 | 1557 | 2.3 | 2.55E-02 |
| [Smad3] MAD homolog 3 (Drosophila) | 593 | 1339 | 2.3 | 2.35E-02 |
| [2810002D19Rik] RIKEN cDNA 2810002D19 gene | 239 | 530 | 2.2 | 1.10E-02 |
| [Phf6] PHD finger protein 6 | 527 | 1154 | 2.2 | 1.06E-02 |
| [Hsd17b11] hydroxysteroid (17-beta) dehydrogenase 11 | 386 | 813 | 2.1 | 3.18E-02 |
| [6720457D02Rik] RIKEN cDNA 6720457D02 gene | 963 | 2023 | 2.1 | 4.95E-02 |
| [Yipf7] Yip1 domain family, member 7 | 705 | 1463 | 2.1 | 1.59E-02 |
| [Mep1a] meprin 1 alpha | 375 | 765 | 2.0 | 3.87E-02 |
| [Sox15] SRY-box containing gene 15 | 318 | 648 | 2.0 | 4.73E-02 |
| [4930473M17Rik] RIKEN cDNA 4930473M17 gene | 421 | 845 | 2.0 | 3.03E-03 |
This table shows the 20 most induced mRNA transcripts in exosomes derived from MC/9 cells exposed to oxidative stress (H2O2, 125 µM for 24 h, oxi exo) compared to exosomal mRNA transcripts after exposure of cells to vehicle (norm exo). A fold-change of e.g. 2 indicated that the gene is 2 fold up-regulated in the exosomes derived from cells exposed to oxidative stress.