Table 2. Clinical characteristics of families RP50 and W09–0046.
| VA at current age | VA at the time of diagnosis | |||||||
|---|---|---|---|---|---|---|---|---|
|
Family |
Patient |
Current age |
Gender |
Age of Onset |
RE (OD) |
LE (OS) |
RE (OD) |
LE (OS) |
| RP50 |
IV:4 |
42 |
Female |
12–15 |
20/630 |
20/630 |
20/400 |
20/400 |
| |
IV:6 |
40 |
Male |
12–15 |
20/125 |
20/400 |
20/125 |
20/125 |
| W09–0046 |
IV:3 |
48 |
Male |
16–18 |
ND |
ND |
20/400 |
20/400 |
| IV:4 | 42 | Male | 16–18 | ND | ND | 20/400 | 20/400 | |
The table indicates the loss of visual acuity which points toward the macular degeneration. For family RP50, the comparison between the readings taken at an earlier and later time points, point toward the rapid progression of the disease. Current age is indicated in the table while the age at the time of diagnosis for individuals IV:4 and IV:6 from RP50 were 40 and 38 years and for IV:3 and IV:4 from family W09–0046, were 46 and 40, respectively. Abbreviations: VA, uncorrected visual acuity; ND, not determined; RE, right eye; LE, left eye.