. Author manuscript; available in PMC: 2012 Jan 1.

Published in final edited form as: Environ Mol Mutagen. 2011 Jan;52(1):58–68. doi: 10.1002/em.20581

TABLE II.

Comparison of DNA damage in Group 2 human placenta determined by IHC, ³²P-postlabeling and abasic site analysis

ID	IHC Total Nuclei Counted	IHC/ACIS Adducts/ 10⁸ Nucleotides	³²P-Postlabeling Adducts/ 10⁸ Nucleotides	Abasic sites/ 10⁵ Nucleotides^c	ETS^b Exposure
Smokers
3019	110	-^a	6.7	7.95 ± 0.42	+
3026	165	-^a	6.7	18.27 ± 0.08	+
3027	143	-^a	7.2	13.63 ± 0.32	+
3034	101	-^a	7.5	9.62 ± 0.22	+
3040	116	-^a	8.6	7.70 ± 0.12	+
3043	108	-^a	1.8	9.43 ± 0.03	+
3049	107	-^a	3.2	15.02 ± 0.43	+
3059	104	-^a	4.8	36.63 ± 0.45	+
3061	103	0.23	4.4	13.78 ± 0.64	+
3078	105	0.72	3.6	7.42 ± 0.36	+
3082	126	-^a	3.6	11.60 ± 0.33	+
3084	113	-^a	6.0	29.43 ± 1.18	+
3086	105	-^a	5.6	3.90 ± 0.35	+
3089	219	1.10	5.6	2.32 ± 0.16	+
3096	216	-^a	4.0	12.13 ± 0.95	+
3101	209	1.21	1.7	10.60 ± 1.15	+
3102	223	3.14	2.6	5.15 ± 0.17	+
3108	224	-^a	6.2	10.13 ± 0.08	+
Non-Smokers
3017	198	-^a	5.7	44.35 ± 1.0	+
3020	114	-^a	6.0	6.63 ± 0.40	+
3024	103	-^a	6.4	13.67 ± 0.27	+
3032	141	0.09	6.8	0.58 ± 0.12	+
3038	111	-^a	7.5	13.53 ± 0.70	+
3041	108	-^a	1.8	21.70 ± 1.06	+
3044	118	-^a	4.3	12.15 ± 1.13	+
3066	114	-^a	7.7	7.95 ± 0.23	+
3103	203	0.15	3.4	9.07 ± 0.82	+
3018	114	-^a	6.2	9.55 ± 0.53	−
3060	194	-^a	5.6	47.15 ± 0.93	−
3068	216	5.91	2.7	10.93 ± 0.75	−
3076	112	-^a	3.3	7.22 ± 0.42	−
3077	100	-^a	3.5	6.65 ± 0.48	−
3083	112	-^a	2.3	7.95 ± 0.70	−
3085	208	-^a	3.7	7.28 ± 0.38	−
3091	210	2.46	4.5	8.80 ± 0.14	−
3094	205	0.01	5.1	6.62 ± 0.39	−
3100	216	-^a	4.4	9.90 ± 0.11	−

Below limit of detection (0.01 adducts/10⁸ nucleotides)

ETS = Environmental Tobacco Smoke exposure, self-reported. “+” = yes, “−” = no

Mean ± SD (n = 3 assays)