Table 3. Results from haplogroup association analysis for ischemic stroke.
| Haplogroup | Frequencies | OR | 95% CI | p | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGH | ISGS-SWISS | GCNKSS | JUSS | GEOS | |||||||||
| Cases | Ctrls | Cases | Ctrls | Cases | Ctrls | Cases | Ctrls | Cases | Ctrls | ||||
| H | 0.40 | 0.41 | 0.41 | 0.42 | 0.43 | 0.42 | 0.36 | 0.36 | 0.40 | 0.42 | 0.98 | 0.88 – 1.09 | 0.65 |
| H1 | 0.13 | 0.15 | 0.14 | 0.15 | 0.15 | 0.14 | 0.12 | 0.11 | 0.15 | 0.15 | 0.97 | 0.91 – 1.04 | 0.41 |
| H2 | 0.27 | 0.25 | 0.26 | 0.28 | 0.28 | 0.27 | 0.24 | 0.25 | 0.25 | 0.27 | 1.05 | 0.90 – 1.23 | 0.52 |
| J | 0.09 | 0.09 | 0.10 | 0.09 | 0.09 | 0.10 | 0.08 | 0.08 | 0.10 | 0.09 | 1.02 | 0.99 – 1.04 | 0.15 |
| K | 0.07 | 0.06 | 0.06 | 0.06 | 0.06 | 0.07 | 0.05 | 0.06 | 0.05 | 0.06 | 1.03 | 0.90 – 1.20 | 0.68 |
| preHV | 0.05 | 0.06 | 0.05 | 0.06 | 0.07 | 0.04 | 0.06 | 0.07 | 0.07 | 0.06 | 0.86 | 0.82 – 1.08 | 0.39 |
| T | 0.09 | 0.09 | 0.08 | 0.09 | 0.08 | 0.10 | 0.09 | 0.09 | 0.10 | 0.08 | 0.97 | 0.86 – 1.10 | 0.66 |
| U | 0.15 | 0.15 | 0.14 | 0.15 | 0.15 | 0.16 | 0.19 | 0.18 | 0.14 | 0.16 | 1.00 | 0.81 – 1.22 | 0.99 |
| WX | 0.03 | 0.04 | 0.04 | 0.04 | 0.05 | 0.04 | 0.03 | 0.04 | 0.03 | 0.04 | 1.09 | 0.96 – 1.23 | 0.18 |
| I | 0.03 | 0.02 | 0.02 | 0.03 | 0.02 | 0.02 | 0.03 | 0.02 | 0.04 | 0.04 | 1.02 | 0.95 – 1.10 | 0.68 |
CI = confidence interval, Ctrls = controls, GCNKSS = Greater Cincinnati Northern Kentucky Stroke Study, GEOS = University of Maryland Genetics of Early Onset Stroke Study, ISGS/SWISS = Ischemic Stroke Genetic Study/Siblings with Ischemic Stroke Study, JUSS = Jagiellonian University Stroke Study, MGH = Massachusetts General Hospital Ischemic Stroke Genome-wide Association Study, OR = odds ratio