. 2010 Oct 20;119(1):189–208. doi: 10.1093/toxsci/kfq314

TABLE 11.

Coplanar PCB Congener Analysis on PND13*

Genotype	Tissue	PCB 77	PCB 126	PCB 169
Ahr^b1Cyp1a2(+/+)	Maternal brain	< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(+/+)		0.5 ± 0.5	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		1.7 ± 0.6	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Maternal liver	< 0.5	4.5 ± 1.4	2.4 ± 0.7
Ahr^dCyp1a2(+/+)		< 0.5	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		0.9 ± 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		1.5 ± 0.1	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Maternal inguinal fat pad	3.3 ± 2.1	1.0 ± 0.6	35.6 ± 11
Ahr^dCyp1a2(+/+)		10.4 ± 0.8	1.2 ± 0.8	34.9 ± 1.8
Ahr^b1Cyp1a2(−/−)		33.9 ± 6.1	5.3 ± 2.9	69.4 ± 11
Ahr^dCyp1a2(−/−)		35.9 ± 12	0.9 ± 0.6	15.0 ± 8.8
Ahr^b1Cyp1a2(+/+)	Maternal mammary tissue	< 0.5	< 0.5	1.8 ± 1.1
Ahr^dCyp1a2(+/+)		1.2 ± 0.2	< 0.5	1.9 ± 0.3
Ahr^b1Cyp1a2(−/−)		3.1 ± 0.6	< 0.5	10.8 ± 2.4
Ahr^dCyp1a2(−/−)		3.2 ± 0.6	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Pup brain	< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(+/+)		3.1 ± 1.0	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		13.6 ± 6.9	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Pup liver	1.0 ± 0.7	22.6 ± 4.1	31.9 ± 3.1
Ahr^dCyp1a2(+/+)		11.6 ± 2.7	1.2 ± 0.6	2.3 ± 0.3
Ahr^b1Cyp1a2(−/−)		0.9 ± 0.5	1.2 ± 0.4	11.6 ± 1.7
Ahr^dCyp1a2(−/−)		46.5 ± 16	< 0.5	1.4 ± 1.2
Ahr^b1Cyp1a2(+/+)	Pup total adipose tissue	2.4 ± 0.7	2.1 ± 0.5	50.0 ± 4.8
Ahr^dCyp1a2(+/+)		106 ± 16	6.4 ± 0.5	40.7 ± 4.1
Ahr^b1Cyp1a2(−/−)		19.1 ± 1.0	14.4 ± 1.0	96.0 ± 6.3
Ahr^dCyp1a2(−/−)		408 ± 32	3.6 ± 1.5	24.7 ± 12
Ahr^b1Cyp1a2(+/+)	Pup plasma	< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(+/+)		2.0 ± 0.2	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		< 0.5	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		8.2 ± 0.8	< 0.5	< 0.5

Note. These tissues were collected 8 days after the second gavage to the mother on PND5.