TABLE 4.
Assessment of Birth Weights and Neonatal Lethality
| Genotype | Treatment | Birth weight (g) | Dystocia cases (% pregnancies) | Abnormal gestation (% pregnancies)a | Litter size | Neonatal lethality (%) |
| Ahrb1_Cyp1a2(+/+) | Corn oil | 1.33 ± 0.01 | 0 | 5.9 | 7.8 ± 0.3 | 6.8 |
| Ahrb1_Cyp1a2(+/+) | PCB | 1.32 ± 0.01 | 18 | 5.3 | 8.3 ± 0.5 | 15 |
| Ahrd_Cyp1a2(+/+) | Corn oil | 1.32 ± 0.01 | 6.7 | 0 | 8.1 ± 0.3 | 3.5 |
| Ahrd_Cyp1a2(+/+) | PCB | 1.33 ± 0.01 | 16 | 0 | 7.7 ± 0.4 | 13 |
| Ahrb1_Cyp1a2(−/−) | Corn oil | 1.30 ± 0.01 | 0 | 0 | 7.9 ± 0.4 | 8.7 |
| Ahrb1_Cyp1a2(−/−) | PCB | 1.27 ± 0.01* | 21 | 22 | 7.0 ± 0.4 | 14 |
| Ahrd_Cyp1a2(−/−) | Corn oil | 1.32 ± 0.02 | 0 | 0 | 7.6 ± 0.4 | 12 |
| Ahrd_Cyp1a2(−/−) | PCB | 1.28 ± 0.01* | 26 | 21 | 8.0 ± 0.4 | 21 |
Note. All values are expressed as means ± SEM.
a
Abnormal gestation refers to pregnancies that ended prematurely or were prolonged beyond the normal 19.5-day gestational length.
*
Significantly different from all other groups. p < 0.001; N was ≥ 10 litters per group.