. 2010 Oct 20;119(1):189–208. doi: 10.1093/toxsci/kfq314

TABLE 8.

Noncoplanar PCB Congener Analysis on GD18.5

Genotype	Tissue	PCB 105	PCB 118	PCB 138	PCB 153	PCB 180
Ahr^b1Cyp1a2(+/+)	Maternal brain	29.4 ± 3.2	30.8 ± 2.5	31.1 ± 2.5	23.1 ± 2.3	32.4 ± 2.4
Ahr^dCyp1a2(+/+)		33.1 ± 2.6	33.2 ± 4.8	30.6 ± 4.8	23.5 ± 3.4	34.4 ± 6.0
Ahr^b1Cyp1a2(−/−)		33.4 ± 2.4	32.4 ± 3.3	29.2 ± 2.8	22.5 ± 2.7	32.1 ± 3.6
Ahr^dCyp1a2(−/−)		34.4 ± 2.2	32.6 ± 1.5	30.4 ± 1.6	23.3 ± 1.1	33.0 ± 2.2
Ahr^b1Cyp1a2(+/+)	Maternal liver	164 ± 4.5	129 ± 5.0	148 ± 4.0	76.1 ± 21	136 ± 5.5
Ahr^dCyp1a2(+/+)		127 ± 16.7	89.7 ± 13	98.9 ± 16	64.4 ± 10	94.0 ± 16
Ahr^b1Cyp1a2(−/−)		145 ± 16	97.5 ± 12	132 ± 14	69.1 ± 10	121 ± 14
Ahr^dCyp1a2(−/−)		126 ± 13	87.9 ± 9.3	109 ± 11	65.4 ± 7.0	107 ± 13
Ahr^b1Cyp1a2(+/+)	Maternal inguinal fat pad	639 ± 38	580 ± 38	570 ± 37	448 ± 36	482 ± 34
Ahr^dCyp1a2(+/+)		691 ± 56	614 ± 49	586 ± 51	475 ± 40	515 ± 49
Ahr^b1Cyp1a2(−/−)		740 ± 91	657 ± 84	626 ± 79	502 ± 70	541 ± 67
Ahr^dCyp1a2(−/−)		678 ± 43	599 ± 34	559 ± 39	445 ± 29	478 ± 43
Ahr^b1Cyp1a2(+/+)	Maternal mammary tissue	514 ± 31	477 ± 31	485 ± 34	386 ± 32	432 ± 38
Ahr^dCyp1a2(+/+)		575 ± 49	516 ± 38	507 ± 44	411 ± 35	486 ± 47
Ahr^b1Cyp1a2(−/−)		495 ± 56	449 ± 53	436 ± 53	353 ± 47	412 ± 56
Ahr^dCyp1a2(−/−)		566 ± 42	508 ± 33	496 ± 41	401 ± 31	465 ± 53
Ahr^b1Cyp1a2(+/+)	Fetal brain	20.8 ± 1.5	21.5 ± 1.0	21.3 ± 1.1	16.3 ± 1.0	19.8 ± 1.0
Ahr^dCyp1a2(+/+)		18.1 ± 3.3	16.7 ± 3.1	15.3 ± 3.2	12.3 ± 2.6	14.8 ± 3.3
Ahr^b1Cyp1a2(−/−)		20.4 ± 2.5	19.3 ± 2.5	17.9 ± 2.7	14.2 ± 2.4	17.9 ± 2.8
Ahr^dCyp1a2(−/−)		25.4 ± 5.2	24.3 ± 4.6	22.1 ± 4.4	17.3 ± 3.5	20.5 ± 3.8
Ahr^b1Cyp1a2(+/+)	Fetal liver	47.2 ± 5.5	34.9 ± 5.0	41.9 ± 5.3	26.3 ± 4.0	34.1 ± 4.5
Ahr^dCyp1a2(+/+)		37.4 ± 7.7	26.6 ± 6.1	29.0 ± 6.8	19.4 ± 4.9	26.6 ± 7.2
Ahr^b1Cyp1a2(−/−)		36.9 ± 5.3	23.7 ± 3.9	28.3 ± 4.8	16.7 ± 3.3	24.2 ± 4.8
Ahr^dCyp1a2(−/−)		37.6 ± 3.3	25.3 ± 2.1	30.0 ± 1.9	17.9 ± 1.4	25.3 ± 2.4

Note. These tissues were collected 8 days after the first gavage on GD10.5.