. 2010 Oct 20;119(1):189–208. doi: 10.1093/toxsci/kfq314

TABLE 9.

Coplanar PCB Congener Analysis on PND6

Genotype	Tissue	PCB 77	PCB 126	PCB 169
Ahr^b1Cyp1a2(+/+)	Maternal brain	0.7 ± 0.7	< 0.5	< 0.5
Ahr^dCyp1a2(+/+)		9.8 ± 2.0	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		3.2 ± 0.8	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		10.0 ± 1.1	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Maternal liver	11.5 ± 1.8	3.1 ± 2.0	18.1 ± 1.9
Ahr^dCyp1a2(+/+)		43.2 ± 8.8	0.7 ± 0.7	2.3 ± 0.6
Ahr^b1Cyp1a2(−/−)		10.0 ± 4.3	< 0.5	2.7 ± 1.6
Ahr^dCyp1a2(−/−)		36.6 ± 6.0	< 0.5	1.3 ± 0.7
Ahr^b1Cyp1a2(+/+)	Maternal inguinal fat pad	122 ± 19	8.1 ± 0.2	43.6 ± 1.4
Ahr^dCyp1a2(+/+)		271 ± 27	5.4 ± 1.8	34.5 ± 7.9
Ahr^b1Cyp1a2(−/−)		200 ± 7.9	1.7 ± 0.2	39.7 ± 5.4
Ahr^dCyp1a2(−/−)		304 ± 11	4.4 ± 2.0	22.2 ± 1.7
Ahr^b1Cyp1a2(+/+)	Maternal mammary tissue	26.4 ± 14	0.8 ± 0.2	14.3 ± 4.1
Ahr^dCyp1a2(+/+)		172 ± 36	4.1 ± 3.1	14.9 ± 5.5
Ahr^b1Cyp1a2(−/−)		64.8 ± 22	< 0.5	22.4 ± 6.8
Ahr^dCyp1a2(−/−)		164 ± 36	1.2 ± 0.3	12.0 ± 0.7
Ahr^b1Cyp1a2(+/+)	Pup brain	1.2 ± 0.7	< 0.5	< 0.5
Ahr^dCyp1a2(+/+)		11.6 ± 0.5	< 0.5	< 0.5
Ahr^b1Cyp1a2(−/−)		2.2 ± 0.1	< 0.5	< 0.5
Ahr^dCyp1a2(−/−)		10.8 ± 1.0	< 0.5	< 0.5
Ahr^b1Cyp1a2(+/+)	Pup liver	30.5 ± 3.8	2.9 ± 2.0	24.7 ± 6.3
Ahr^dCyp1a2(+/+)		59.5 ± 8.2	0.6 ± 0.3	4.2 ± 1.6
Ahr^b1Cyp1a2(−/−)		21.5 ± 1.6	0.8 ± 0.2	11.4 ± 4.5
Ahr^dCyp1a2(−/−)		121 ± 28	0.7 ± 0.4	31.5 ± 7.9
Ahr^b1Cyp1a2(+/+)	Pup total adipose tissue	52.5 ± 10	1.4 ± 0.7	26.0 ± 3.3
Ahr^dCyp1a2(+/+)		182 ± 30	2.8 ± 0.4	22.8 ± 9.1
Ahr^b1Cyp1a2(−/−)		109 ± 9.7	1.0 ± 0.3	18.8 ± 10
Ahr^dCyp1a2(−/−)		339 ± 59	2.8 ± 1.4	20.5 ± 11
Ahr^b1Cyp1a2(+/+)	Pup stomach	48.4 ± 20	1.6 ± 0.9	15.6 ± 2.9
Ahr^dCyp1a2(+/+)		169 ± 29	2.7 ± 1.3	10.5 ± 4.9
Ahr^b1Cyp1a2(−/−)		101 ± 13	0.7 ± 0.3	18.9 ± 2.7
Ahr^dCyp1a2(−/−)		225 ± 26	1.8 ± 0.5	21.7 ± 4.3

Note. These tissues were collected 24 h after the second gavage on PND5.