Skip to main content
. Author manuscript; available in PMC: 2010 Dec 18.
Published in final edited form as: Cancer Res. 2009 Sep 29;69(19):7662–7671. doi: 10.1158/0008-5472.CAN-09-1693

Figure 5.

Figure 5

VEGF levels in control and treated tumor xenografts

Mice received CP-751,871 (0.5 mg/mouse) twice weekly, rapamycin daily 5-days per week or the combination. Tumors were harvested 1 hr after the last dose of rapamycin, and snap-frozen in liquid N2. Extracts were prepared from tumors and VEGF determined by a human-specific ELISA as described in Experimental Procedures. For each condition (control, CP-751,871, rapamycin or the combination) 6 to 9 independent determinations were used at each time point. * indicates significantly different from controls (P<0.05).
  1. EWS xenografts.
  2. OS xenografts.