Table 3.

Chimerism in BN recipients 30 and 100 days after transplantation of LEW organs or leukocyte suspensions under a short course of tacrolimus^a

	30 Days			100 Days
	Flow cytometry (class I)b	Immunohistochemistry (class II)c	Lineage	Immunocytochemistry (class II)e	Tolerance	GVHD
Small bowel	4.0±2.3%d	+ + +	T > Me	—	No	100%
Lymph nodes	4.1±1.8%	+ + +	T > M	—	No	100%
Spleen	7.5±0.2%	+ + +	T > M	—	Minimalf	100%
Liver	<1.0%	+ +	M = T	±	Yes	0
Bone marrow	0	+	M > T	±	Yes	0
Heart	0	±	—	−	Partialg	0
Kidney	NT	±	—	−	NT	0
Thymus	NT	−	—	−	No	0
Blood	NT	−	—	−	No	0

^a1.0 mg/kg/day on days 0 to 13; 20, and 27.

^bMcAb 163, blood samples, or recipient lymph node suspensions.

^cL-21-6Ab, spleen, and cervical lymph nodes.

^dMean ± SD.

^eNT: not tested; M: multilineage; T: T lymphocyte.

^fDelayed acute rejection.

^gChronic rejection.