Table 5.
MLR against BN (syngeneic), LEW (donor), and ACI (third-party) in naive and bone marrow–, whole blood–, or thymocyte-primed BN ratsa
BN responderb | Stimulator |
||
---|---|---|---|
BN (syngeneic) | LEW (donor) | ACI (third-party) | |
Naive | 235±78 | 36.558±1844 | 26.979±6276 |
Bone marrow | 703±184 | 21.122±5176 | 24.450±12.367 |
Blood | 965±449 | 30.983±5215 | 36.020±7877 |
Thymus | 911±55 | 15.651±4454 | 17.842±4181 |
All values are mean ± SD (cpm) of triplicate wells.
BN animals received bone marrow, thmocytes (250× l06) or 3 ml whole blood from LEW (day 0) and were treated with tacrolimus (1.0 mg/kg/day on days 0 to 13 and 20, and 27). Cervical lymph nodes were obtained on day 100 for analysis.