. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Drug Discov Today Dis Mech. 2010 SUMMER;7(2):e109–e115. doi: 10.1016/j.ddmec.2010.07.004

Table 1.

randomized, double blinded, controlled clinical trials for stem cell transplantation

Trial	No. of patients	Treatment	Follow up (months)	Follow up (method)	Change in LVEF (%) (Treatment vs. control)	p-value
MAGIC [10]	97	myoblasts	6	ECHO	3.4(−0.3; 12.4)/5.2(−4.4; 11) vs. 4.4(0.2; 7.3)	NS
REPAIR-AMI [57]	204	BMC	4	LV-Angio	5.5±7.3 vs. 3.0±6.5	<0.01
Janssens [58]	67	BMC	4	MRI	3.4±6.9 vs. 2.2±7.3	NS
BOOST^* [59, 60]	60	BMC	6/60	MRI	6.7±6.5 vs. 0.7±8.1/−2.5±11.9 vs. −3.3±9.5	0.003/NS
Chen [61]	69	BMMC	6	LV-Angio	18 vs 6	0.01

BMC= bone marrow stem cells

BMMC = bone marrow mesenchymal stem cells

LVEF = left ventricular ejection fraction

LV-Angio = left ventricular angiography

MRI = magnetic resonance imagin

NS = not significant

= not double blinded